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Natural Products - Drug Development

Author Name : K. Tayung, A. Puratchikody and S. Ramakrishnan

Features

  • Publisher : Studium Press India Pvt Ltd
  • Edition : 1st
  • ISBN 13 : 978-93-80012-65-0
  • Page no : 560
  • Publication Year : 2014
$34

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  • Description
  • Table Of Content
  • Reviews
The impor¬tance of natural products for medicine and health has been enormous. Due to diverse biological activities and medicinal potentials of natural products, nearly every civilization has accumulated experience and knowledge of their use. During the last two decades, research aimed at exploiting natural products as a resource has seriously declined. This is in part due to the development of new technologies such as combinatorial chemistry, metagenomics and high-throughput screening. However, the new drug discovery approaches did not fulfilled the initial expectations. This has lead to a renewed interest in natural products, determined by the urgent need for new drugs, in particular to fight against infections caused by multi-resistant pathogens. Besides, untapped biological resources, “smart screening” methods, robotic separation with structural analysis, metabolic engineering, and synthetic biology offer exciting technologies for new natural product drug discovery. However, one of the greatest challenges is to identify natural compounds or naturally inspired compounds that can be combined to be effective against human diseases. Thus, the mod¬ern pharmaceutical researches today use powerful tools of genomics, proteomics, metabolomics, synthetic and combinatorial chemistry for development of new candidature drug. The book “NATURAL PRODUCTS-DRUG DEVELOPMENT” provides the reader with recent information on drug discovery from natural sources and its development using mod¬ern pharmaceutical research tools. The contributors are eminent subject experts working in the field of product development from natural sources such as plants, animals or microorganisms. The most remarkable feature of this book is the biotechnological and pharmaceutical approaches and structure elucidation of active molecules. This book would cater the need of graduate and post graduate students pursuing their study in all branches of life-sciences, pharmaceutical sciences, researchers and scientists working in the laboratories and industries involved in natural product discovery
Title Natural Products - Drug Development
Table of Content Forward, Preface, List of contributors. Section I: MICROBIAL DRUG DISCOVERY: Bioprospecting Soil Microorganisms for Novel Bioactive Metabolites, Microalgae: A Potential Source of Bioactive Metabolites, Diversity of Wild Mushrooms and its Medicinal Uses, Endolichenic Fungi as a Source of Novel Bioactive Metabolites: Present and Future Prospects, Endophytic Fungi of Medicinal Plants as a Source of Novel Bioactive Compounds. Section II: BIOACTIVE METABOLITES FROM PLANTS THROUGH IN VITRO CULTURES: Changing Socio-Cultural Perspectives on the Use of Phytotherapeutics, Screening of Antibacterial Potential of Medicinal Plants, Biotechnology and Herbal Medicine, Plant Cell Culture – An Efficient Source of Secondary Metabolites, Root Culture for Secondary Metabolites Production, Micro RNAs as Therapeutic Molecules for the Effective Treatment of Diseases, Transgenic Plants in Biopharming. Section III: DEVELOPMENT OF PHARMACEUTICAL DRUGS: Natural Products in Drug Discovery and Development: An Overview, Computer Aided Drug Design, Retrosynthesis in the Chemistry of Natural Products-I, Retro Synthesis in the Chemistry of Natural Products-II, Structural Elucidation of Small Molecules: IR- 1H NMR-13CNMR – Mass Spectra, Subject Index.
Page No. 560
Author's Name K. Tayung, A. Puratchikody and S. Ramakrishnan
Publisher Studium Press India Pvt Ltd
Year Of Publication 2014
ISBN 10 No
ISBN 13 978-93-80012-65-0
About The Book No
Binding type No
Book Size(len) No
Series No
book size(hei) 10
Book size width 7.5
Edition 1st

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